Claire Redfield

(First Appearence: Resident Evil 2)
Sisters are doing it for themselves.
Hugely attractive, motorbike riding, gunslinging sisters that is. Not just any sister, but the sister of STARS member extraordinairre Chris Redfield.
As the Raccoon city incident unfolds, Claire Redfield rides into town looking for her brother who she has not heard from in quite sometime. Upon arriving, Claire enters a diner where she is attacked by infected citizens. Escaping through the back alley, Claire runs right into the gun barrel of pretty-boy cop Leon Kennedy, after a huge, out of control tanker puts paid to their escape plans. Claire and Leon are seperated and take refuge inside a seemingly abandoned Police station.

So begins Resident Evil 2, one of the finest games ever made and so begins Claire's story. Young Redfield quickly adapts to her situation and makes moves to keep not only herself out of danger but also provide maternal safety for Sherry Birkin, a young girl whose mother has become a gun waving psycho and whose father has a giant-ass eye sticking out his arm.
Upon escaping the station and huge underground complex within. Claire immediatly sets about finding her brother and uncovering Umbrella's scheme. Redfield travels to Umbrella's Paris laboratory where she is captured and imprisoned on Rockfort Island.

Fate intervenes again and a viral outbreak on the island allows our heorine to escape her cell and continue her search for Chris. Alongside Steve Burnside, the world's most singulary annoying videogame character of all time. Claire travels to Antartica where she finally catches up with her brother and they together they put an end to the current wave of Umbrella scheming and corruption.

Claire is a great heroine, she is vulnerable but brave. Claire begins her adventure fairly naive but by the timeline of Code: Veronica is already deeply involved in industrial espionage. Claire clearly has a deep bond with her brother and goes to very dangerous lengths in order to to find him.
Claire's girl next door good looks belie her iron will and mental toughness. Possibly the least glamourous of the Resi girls, Claire is potentially the most relatable and the easiest to connect with.

I don't know what the Redfield parents had in their genes, but they produced some damn cool offspring. Claire has not appeared in a fresh adventure in the main Resident Evil canon for some years, but I'm sure many would join my call that maybe it's time for the fairer Redfield to don her burgandy waistcoat once again.